Distinct COVID-19 vaccine combinations result in divergent immune responses
Preprint
Written by Luca M. Zaeck, Ngoc H. Tan, Wim J.R. Rietdijk, Daryl Geers, Roos S.G. Sablerolles, Susanne Bogers, Laura L.A. van Dijk, Lennert Gommers, Leanne P.M. van Leeuwen, Sharona Rugebregt, Abraham Goorhuis, Douwe F. Postma, Leo G. Visser, Virgil A.S.H. Dalm, Melvin Lafeber, Neeltje A. Kootstra, Anke L.W. Huckriede, Bart L. Haagmans, Debbie van Baarle, Marion P.G. Koopmans, P. Hugo M. van der Kuy, Corine H. GeurtsvanKessel, Rory D. de Vries, - SWITCH-ON Research Group
August 25, 2023
Waning antibody responses after COVID-19 vaccination combined with the emergence of the SARS-CoV-2 Omicron lineage led to reduced vaccine effectiveness. As a countermeasure, bivalent mRNA-based booster vaccines encoding the ancestral…