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Wastewater Detection of COVID-19

Missouri State Dept/ Health & Senior Services

Jeff Wenzel

Wastewater
Website

Related publications

Genetic Diversity and Evolutionary Convergence of Cryptic SARS-CoV-2 Lineages Detected Via Wastewater Sequencing

Written by Devon A Gregory, Monica Trujillo, Clayton Rushford, Anna Flury, Sherin Kannoly, Kaung Myat San, Dustin Lyfoung, Roger W Wiseman, Karen Bromert, Ming-Yi Zhou, Ellen Kesler, Nathan Bivens, Jay Hoskins, Chung-Ho Lin, David O'Connor, Chris Wieberg, Jeff Wenzel, Rose S Kantor, John J Dennehy, Marc Johnson
June 3, 2022

Wastewater-based epidemiology (WBE) is an effective way of tracking the appearance and spread of SARS-COV-2 lineages through communities. Beginning in early 2021, we implemented a targeted approach to amplify and…

Characterization of SARS-CoV-2 Genetic Material in Wastewater

Written by Carolyn A Robinson, Hsin-yeh Hsieh, Shu Yu Hsu, Yang Wang, Braxton Salcedo, Jessica Klutts, Sally Zemmer, Anthony Belenchia, Melissa Reynolds, Elizabeth Semkiw, Trevor Foley, Xiu-feng Wan, Chris Wieberg, Jeff Wenzel, Chung-Ho Lin, Marc C Johnson
July 25, 2021

SARS-CoV-2 genetic material has been detected in raw wastewater around the world throughout the COVID-19 pandemic and has served as a useful tool for monitoring community levels of SARS-CoV-2 infections.…

Defining biological and biophysical properties of SARS-CoV-2 genetic material in wastewater.

Written by Carolyn A Robinson, Hsin-Yeh Hsieh, Shu-Yu Hsu, Yang Wang, Braxton T Salcedo, Anthony Belenchia, Jessica Klutts, Sally Zemmer, Melissa Reynolds, Elizabeth Semkiw, Trevor Foley, XiuFeng Wan, Chris G Wieberg, Jeff Wenzel, Chung-Ho Lin, Marc C Johnson
February 10, 2022

SARS-CoV-2 genetic material has been detected in raw wastewater around the world throughout the COVID-19 pandemic and has served as a useful tool for monitoring community levels of SARS-CoV-2 infections.…

Monitoring SARS-CoV-2 Populations in Wastewater by Amplicon Sequencing and Using the Novel Program SAM Refiner.

Written by Devon A Gregory, Chris G Wieberg, Jeff Wenzel, Chung-Ho Lin, Marc C Johnson
August 19, 2021

Sequencing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) from wastewater has become a useful tool in monitoring the spread of viral variants. Approaches to this task have been varied, relying…

Monitoring SARS-CoV-2 Populations in Wastewater by Amplicon Sequencing and Using the Novel Program SAM Refiner

Written by Devon A Gregory, Chris G Wieberg, Jeff Wenzel, Chung-Ho Lin, Marc C Johnson
June 26, 2021

Sequencing SARS-CoV-2 from wastewater has become a useful tool in monitoring the spread of variants. We use a novel computation workflow with SARS-CoV-2 amplicon sequencing in order to track wastewater…

Identification and Quantification of Bioactive Compounds Suppressing SARS-CoV-2 Signals in Wastewater-based Epidemiology Surveillance

Written by Mohamed Bayati, Hsin-Yeh Hsieh, Shu-Yu Hsu, Elizabeth Rogers, Anthony Belenchia, Sally A. Zemmer, Todd Blanc, Cindy LePage, Jessica Klutts, Melissa Reynolds, Elizabeth Semkiw, Hwei-Yiing Johnson, Trevor Foley, Chris G. Wieberg, Jeff Wenzel, Terri Lyddon, Mary LePique, Clayton Rushford, Braxton Salcedo, Kara Young, Madalyn Graham, Reinier Suarez, Anarose Ford, Zhentian Lei, Lloyd Sumner, Brian P. Mooney, Xing Wei, C. Michael Greenlief, Marc Johnson, Chung-Ho Lin
March 12, 2022

Recent SARS-CoV-2 wastewater-based epidemiology (WBE) surveillance have documented a positive correlation between the number of COVID-19 patients in a sewershed and the level of viral genetic material in the wastewater.…

Biomarkers Selection for Population Normalization in SARS-CoV-2 Wastewater-based Epidemiology

Written by Shu-Yu Hsu, Mohamed B Bayati, Chenhui Li, Hsin-Yeh Hsieh, Anthony Belenchia, Hweiyiing Johnson, Jessica Klutts, Melissa Reynolds, Elizabeth Semkiw, Jeff Wenzel, Chris Wieberg, Sally A Zemmer, Trevor Foley, Marc Johnson, Chung-Ho Lin
March 15, 2022

Wastewater-based epidemiology (WBE) has been one of the most cost-effective approaches to track the SARS-CoV-2 levels in the communities since the COVID-19 outbreak in 2020. Normalizing SARS-CoV-2 concentrations by the…

Identification and quantification of bioactive compounds suppressing SARS-CoV-2 signals in wastewater-based epidemiology surveillance.

Written by Mohamed Bayati, Hsin-Yeh Hsieh, Shu-Yu Hsu, Chenhui Li, Elizabeth Rogers, Anthony Belenchia, Sally A Zemmer, Todd Blanc, Cindy LePage, Jessica Klutts, Melissa Reynolds, Elizabeth Semkiw, Hwei-Yiing Johnson, Trevor Foley, Chris G Wieberg, Jeff Wenzel, Terri Lyddon, Mary LePique, Clayton Rushford, Braxton Salcedo, Kara Young, Madalyn Graham, Reinier Suarez, Anarose Ford, Zhentian Lei, Lloyd Sumner, Brian P Mooney, Xing Wei, C Michael Greenlief, Marc C Johnson, Chung-Ho Lin
July 5, 2022

Recent SARS-CoV-2 wastewater-based epidemiology (WBE) surveillance have documented a positive correlation between the number of COVID-19 patients in a sewershed and the level of viral genetic material in the wastewater.…

Genetic diversity and evolutionary convergence of cryptic SARS- CoV-2 lineages detected via wastewater sequencing.

Written by Devon A Gregory, Monica Trujillo, Clayton Rushford, Anna Flury, Sherin Kannoly, Kaung Myat San, Dustin T Lyfoung, Roger W Wiseman, Karen Bromert, Ming-Yi Zhou, Ellen Kesler, Nathan J Bivens, Jay Hoskins, Chung-Ho Lin, David H O'Connor, Chris Wieberg, Jeff Wenzel, Rose S Kantor, John J Dennehy, Marc C Johnson
October 14, 2022

Wastewater-based epidemiology (WBE) is an effective way of tracking the appearance and spread of SARS-COV-2 lineages through communities. Beginning in early 2021, we implemented a targeted approach to amplify and…

Population Normalization in SARS-CoV-2 Wastewater-Based Epidemiology: Implications from Statewide Wastewater Monitoring in Missouri

Written by Chenhui Li, Mohamed Bayati, Shu-Yu Hsu, Hsin-Yeh Hsieh, Wilfing Lindsi, Anthony Belenchia, Sally A. Zemmer, Jessica Klutts, Mary Samuelson, Melissa Reynolds, Elizabeth Semkiw, Hwei-Yiing Johnson, Trevor Foley, Chris G. Wieberg, Jeff Wenzel, Terri D. Lyddon, Mary LePique, Clayton Rushford, Braxton B Salcedo, Kara Young, Madalyn Graham, Reinier Suarez, Anarose Ford, Dagmara S. Antkiewicz, Kayley H. Janssen, Martin M. Shafer, Marc C. Johnson, Chung-Ho Lin
September 10, 2022

O_FIG O_LINKSMALLFIG WIDTH=200 HEIGHT=81 SRC="FIGDIR/small/22279459v1_ufig1.gif" ALT="Figure 1"> View larger version (24K): org.highwire.dtl.DTLVardef@debf50org.highwire.dtl.DTLVardef@1e21da2org.highwire.dtl.DTLVardef@78708org.highwire.dtl.DTLVardef@3239ee_HPS_FORMAT_FIGEXP M_FIG C_FIG The primary objective of this study was to identify a universal wastewater biomarker for population normalization…

Biomarkers selection for population normalization in SARS-CoV-2 wastewater-based epidemiology.

Written by Shu-Yu Hsu, Mohamed Bayati, Chenhui Li, Hsin-Yeh Hsieh, Anthony Belenchia, Jessica Klutts, Sally A Zemmer, Melissa Reynolds, Elizabeth Semkiw, Hwei-Yiing Johnson, Trevor Foley, Chris G Wieberg, Jeff Wenzel, Marc C Johnson, Chung-Ho Lin
August 15, 2022

Wastewater-based epidemiology (WBE) has been one of the most cost-effective approaches to track the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) levels in the communities since the coronavirus disease 2019…

Tracing the origin of SARS-CoV-2 Omicron-like Spike sequences detected in wastewater

Written by Martin M Shafer, Devon A Gregory, Max J Bobholz, Adelaide Roguet, Luis A Haddock Soto, Clayton Rushford, William C Vuyk, Kayley H Janssen, Hunter J Ries, Hannah E Pilch, Paige A Mullen, Rebecca B Fahney, Wanting Wei, Matthew Lambert, Jeff Wenzel, Peter Halfmann, Yoshihiro Kawaoka, Nancy A Wilson, Thomas C Friedrich, Ian W Pray, Ryan Westergaard, David H O'Connor, Marc Johnson
October 31, 2022

ImportanceThe origin of highly divergent "cryptic" SARS-CoV-2 Spike sequences, which appear in wastewater but not clinical samples, is unknown. These wastewater sequences have harbored many of the same mutations that…