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Multi-modal Wireless COVID Monitoring & Infection Alerts for Concentrated Populations

Stanford University

Michael Snyder

Multimodal surveillance
Website

Related publications

Early detection of SARS-CoV-2 and other infections in solid organ transplant recipients and household members using wearable devices.

Written by Brendan J Keating, Eyas H Mukhtar, Eric D Elftmann, Feyisope R Eweje, Hui Gao, Lina I Ibrahim, Ranganath G Kathawate, Alexander C Lee, Eric H Li, Krista A Moore, Nikhil Nair, Venkata Chaluvadi, Janaiya Reason, Francesca Zanoni, Alexander T Honkala, Amein K Al-Ali, Fatima Abdullah Alrubaish, Maha Ahmad Al-Mozaini, Fahad A Al-Muhanna, Khaldoun Al-Romaih, Samuel B Goldfarb, Ryan Kellogg, Krzysztof Kiryluk, Sarah J Kizilbash, Taisa J Kohut, Juhi Kumar, Matthew J O'Connor, Elizabeth B Rand, Robert R Redfield, Benjamin Rolnik, Joseph Rossano, Pablo G Sanchez, Arash Alavi, Amir Bahmani, Gireesh K Bogu, Andrew W Brooks, Ahmed A Metwally, Tejas Mishra, Stephen D Marks, Robert A Montgomery, Jay A Fishman, Sandra Amaral, Pamala A Jacobson, Meng Wang, Michael P Snyder
May 5, 2021

The increasing global prevalence of SARS-CoV-2 and the resulting COVID-19 disease pandemic pose significant concerns for clinical management of solid organ transplant recipients (SOTR). Wearable devices that can measure physiologic…

Pre-symptomatic detection of COVID-19 from smartwatch data.

Written by Tejaswini Mishra, Meng Wang, Ahmed A Metwally, Gireesh K Bogu, Andrew W Brooks, Amir Bahmani, Arash Alavi, Alessandra Celli, Emily Higgs, Orit Dagan-Rosenfeld, Bethany Fay, Susan Kirkpatrick, Ryan Kellogg, Michelle Gibson, Tao Wang, Erika M Hunting, Petra Mamic, Ariel B Ganz, Benjamin Rolnik, Xiao Li, Michael P Snyder
November 18, 2020

Consumer wearable devices that continuously measure vital signs have been used to monitor the onset of infectious disease. Here, we show that data from consumer smartwatches can be used for…

Adapting skills from genetic counseling to wearables technology research during the COVID-19 pandemic: Poised for the pivot.

Written by Emily Higgs, Orit Dagan-Rosenfeld, Michael Snyder
September 27, 2021

Genetic counselors have shown themselves to be adaptable in an evolving profession, with expansion into new sub-specialties, various non-clinical settings, and research roles. The COVID-19 pandemic caused a sudden and…

A scalable, secure, and interoperable platform for deep data-driven health management.

Written by Amir Bahmani, Arash Alavi, Thore Buergel, Sushil Upadhyayula, Qiwen Wang, Srinath Krishna Ananthakrishnan, Amir Alavi, Diego Celis, Dan Gillespie, Gregory Young, Ziye Xing, Minh Hoang Huynh Nguyen, Audrey Haque, Ankit Mathur, Josh Payne, Ghazal Mazaheri, Jason Kenichi Li, Pramod Kotipalli, Lisa Liao, Rajat Bhasin, Kexin Cha, Benjamin Rolnik, Alessandra Celli, Orit Dagan-Rosenfeld, Emily Higgs, Wenyu Zhou, Camille Lauren Berry, Katherine Grace Van Winkle, Kévin Contrepois, Utsab Ray, Keith Bettinger, Somalee Datta, Xiao Li, Michael P Snyder
October 1, 2021

The large amount of biomedical data derived from wearable sensors, electronic health records, and molecular profiling (e.g., genomics data) is rapidly transforming our healthcare systems. The increasing scale and scope…

Real-time alerting system for COVID-19 and other stress events using wearable data.

Written by Arash Alavi, Gireesh K Bogu, Meng Wang, Ekanath Srihari Rangan, Andrew W Brooks, Qiwen Wang, Emily Higgs, Alessandra Celli, Tejaswini Mishra, Ahmed A Metwally, Kexin Cha, Peter Knowles, Amir A Alavi, Rajat Bhasin, Shrinivas Panchamukhi, Diego Celis, Tagore Aditya, Alexander Honkala, Benjamin Rolnik, Erika Hunting, Orit Dagan-Rosenfeld, Arshdeep Chauhan, Jessi W Li, Caroline Bejikian, Vandhana Krishnan, Lettie McGuire, Xiao Li, Amir Bahmani, Michael P Snyder
November 29, 2021

Early detection of infectious diseases is crucial for reducing transmission and facilitating early intervention. In this study, we built a real-time smartwatch-based alerting system that detects aberrant physiological and activity…

Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication

Written by Tobias Moll, Valerie Odon, Calum Harvey, Mark Collins, Andrew Peden, John Franklin, Emily Graves, Jack Marshall, Cleide dos Santos Souza, Sai Zhang, Mimoun Azzouz, David Gordon, Nevan Krogan, Laura Ferraiuolo, Michael Snyder, Pamela Shaw, Jan Rehwinkel, Johnathan Cooper-Knock
March 7, 2022

New therapeutic targets are a valuable resource in the struggle to reduce the morbidity and mortality associated with the COVID-19 pandemic, caused by the SARS-CoV-2 virus. Genome-wide association studies (GWAS)…

Common and rare variant analyses combined with single-cell multiomics reveal cell-type-specific molecular mechanisms of COVID-19 severity

Written by Sai Zhang, Johnathan Cooper-Knock, Annika Weimer, Calum Harvey, Thomas Julian, Cheng Wang, Jingjing Li, Simone Furini, Elisa Frullanti, Francesca Fava, Alessandra Renieri, Cuiping Pan, Jina Song, Paul Billing-Ross, Peng Gao, Xiaotao Shen, Ilia Sarah Timpanaro, Kevin Kenna, - VA Million Veteran Program, - GEN-COVID Network, Mark Davis, Philip Tsao, Michael Snyder
June 21, 2021

The determinants of severe COVID-19 in non-elderly adults are poorly understood, which limits opportunities for early intervention and treatment. Here we present novel machine learning frameworks for identifying common and…

Temporal changes in soluble angiotensin-converting enzyme 2 associated with metabolic health, body composition, and proteome dynamics during a weight loss diet intervention: a randomized trial with implications for the COVID-19 pandemic.

Written by Nicholas Cauwenberghs, Mary Prunicki, František Sabovčik, Dalia Perelman, Kévin Contrepois, Xiao Li, Michael P Snyder, Kari C Nadeau, Tatiana Kuznetsova, Francois Haddad, Christopher D Gardner
November 8, 2021

BACKGROUND: Angiotensin-converting enzyme 2 (ACE2) serves protective functions in metabolic, cardiovascular, renal, and pulmonary diseases and is linked to COVID-19 pathology. The correlates of temporal changes in soluble ACE2 (sACE2)…

COVID-19-Induced New-Onset Diabetes: Trends and Technologies.

Written by Ahmed A Metwally, Pranav Mehta, Brian S Johnson, Anvith Nagarjuna, Michael P Snyder
October 22, 2021

The coronavirus disease 2019 (COVID-19) global pandemic continues to spread worldwide with approximately 216 million confirmed cases and 4.49 million deaths to date. Intensive efforts are ongoing to combat this…

A method for intelligent allocation of diagnostic testing by leveraging data from commercial wearable devices: a case study on COVID-19.

Written by Md Mobashir Hasan Shandhi, Peter J Cho, Ali R Roghanizad, Karnika Singh, Will Wang, Oana M Enache, Amanda Stern, Rami Sbahi, Bilge Tatar, Sean Fiscus, Qi Xuan Khoo, Yvonne Kuo, Xiao Lu, Joseph Hsieh, Alena Kalodzitsa, Amir Bahmani, Arash Alavi, Utsab Ray, Michael P Snyder, Geoffrey S Ginsburg, Dana K Pasquale, Christopher W Woods, Ryan J Shaw, Jessilyn P Dunn
September 1, 2022

Mass surveillance testing can help control outbreaks of infectious diseases such as COVID-19. However, diagnostic test shortages are prevalent globally and continue to occur in the US with the onset…

Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.

Written by Tobias Moll, Valerie Odon, Calum Harvey, Mark O Collins, Andrew Peden, John Franklin, Emily Graves, Jack Ng Marshall, Cleide Dos Santos Souza, Sai Zhang, Lydia Castelli, Guillaume Hautbergue, Mimoun Azzouz, David Gordon, Nevan Krogan, Laura Ferraiuolo, Michael P Snyder, Pamela J Shaw, Jan Rehwinkel, Johnathan Cooper-Knock
October 14, 2022

New therapeutic targets are a valuable resource for treatment of SARS-CoV-2 viral infection. Genome-wide association studies have identified risk loci associated with COVID-19, but many loci are associated with comorbidities…

Multiomic analysis reveals cell-type-specific molecular determinants of COVID-19 severity.

Written by Sai Zhang, Johnathan Cooper-Knock, Annika K Weimer, Minyi Shi, Lina Kozhaya, Derya Unutmaz, Calum Harvey, Thomas H Julian, Simone Furini, Elisa Frullanti, Francesca Fava, Alessandra Renieri, Peng Gao, Xiaotao Shen, Ilia Sarah Timpanaro, Kevin P Kenna, J Kenneth Baillie, Mark M Davis, Philip S Tsao, Michael P Snyder
June 3, 2022

The determinants of severe COVID-19 in healthy adults are poorly understood, which limits the opportunity for early intervention. We present a multiomic analysis using machine learning to characterize the genomic…

Deploying wearable sensors for pandemic mitigation: A counterfactual modelling study of Canada's second COVID-19 wave.

Written by Nathan Duarte, Rahul K Arora, Graham Bennett, Meng Wang, Michael P Snyder, Jeremy R Cooperstock, Caroline E Wagner
September 6, 2022

Wearable sensors can continuously and passively detect potential respiratory infections before or absent symptoms. However, the population-level impact of deploying these devices during pandemics is unclear. We built a compartmental…