Innate immune signaling in the olfactory epithelium reduces odorant receptor levels: modeling transient smell loss in COVID-19 patients
Written by Steve Rodriguez, Luxiang Cao, Gregory T. Rickenbacher, Eric G. Benz, Colin Magdamo, Liliana A Ramirez Gomez, Eric Holbrook, Alefiya Dhilla Albers, Rose Gallagher, M. Brandon Westover, Kyle E. Evans, Daniel Tatar, Shibani Mukerji, Ross Zafonte, Edward W. Boyer, C. Ron Yu, Mark W Albers
June 16, 2020
Post-infectious anosmias typically follow death of olfactory sensory neurons (OSNs) with a months-long recovery phase associated with parosmias. While profound anosmia is the leading symptom associated with COVID-19 infection, many…