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Detection and Automatic Privacy-Protected Contact Tracing System Designed for COVID-19

Louisiana State Univ A&M Col Baton Rouge

Lu Peng

Automatic Detection and Tracing
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November 4, 2020

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International metropolises are key sites of outbreaks of COVID-19 cases. Global public evaluation of the pandemic in international cities is affected by many factors. This study examines how media exposure…

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Written by Bing-Hua Chen, Nan-Nan Shi, Chong-Wen Wu, Dong-Aolei An, Yu-Xin Shi, Luke D Wesemann, Jiani Hu, Jian-Rong Xu, Fei Shan, Lian-Ming Wu
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Written by Jian Xu, Cong Liu
October 25, 2021

Objectives: China was believed to be the country with the world's highest acceptance rate of the COVID-19 vaccine following several investigations. This study aims to explore the Chinese acceptance of…

Further divided gender gaps in research productivity and collaboration during the COVID-19 pandemic: Evidence from coronavirus-related literature.

Written by Meijun Liu, Ning Zhang, Xiao Hu, Ajay Jaiswal, Jian Xu, Hong Chen, Ying Ding, Yi Bu
May 5, 2022

Based on publication data on coronavirus-related fields, this study applies a difference in differences approach to explore the evolution of gender inequalities before and during the COVID-19 pandemic by comparing…

Psychological status of surgical staff during the COVID-19 outbreak.

Written by Jian Xu, Qian-Hui Xu, Chang-Ming Wang, Jun Wang
April 11, 2020

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which appeared in early December 2019, had an atypical viral pneumonia outbreak in Wuhan, Hubei, China. And there is a high risk…

Nonmuscle myosin heavy chain IIA facilitates SARS-CoV-2 infection in human pulmonary cells.

Written by Jian Chen, Jun Fan, Zhilu Chen, Miaomiao Zhang, Haoran Peng, Jian Liu, Longfei Ding, Mingbin Liu, Chen Zhao, Ping Zhao, Shuye Zhang, Xiaoyan Zhang, Jianqing Xu
December 14, 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), binds to host receptor angiotensin-converting enzyme 2 (ACE2) through its spike (S) glycoprotein, which mediates…

The Effective Cognitive Assessment and Training Methods for COVID-19 Patients With Cognitive Impairment.

Written by Dong Wen, Jian Xu, Zhonglin Wu, Yijun Liu, Yanhong Zhou, Jingjing Li, Shaochang Wang, Xianlin Dong, M Iqbal Saripan, Haiqing Song
January 11, 2022

Infodemic vs. Pandemic Factors Associated to Public Anxiety in the Early Stage of the COVID-19 Outbreak: A Cross-Sectional Study in China.

Written by Jian Xu, Cong Liu
August 30, 2021

Introduction: Every outbreak of an epidemic or pandemic disease is accompanied by the tsunami of information, which is also known as the infodemic. Infodemic makes it hard for people to…

The Impact of Pandemic Perception, National Feeling, and Media Use on the Evaluation of the Performance of Different Countries in Controlling COVID-19 by Chinese Residents.

Written by Ruixia Han, Jian Xu
July 8, 2021

Different nations responded to the global spread of COVID-19 differently. How do people view the governance practices and effects of various countries? What factors affect their views? Starting from the…

Demand for longer quarantine period among common and uncommon COVID-19 infections: a scoping review.

Written by Zhi-Yao Li, Yu Zhang, Liu-Qing Peng, Rong-Rong Gao, Jia-Rui Jing, Jia-Le Wang, Bin-Zhi Ren, Jian-Guo Xu, Tong Wang
April 26, 2021

BACKGROUND: As one of the non-pharmacological interventions to control the transmission of COVID-19, determining the quarantine duration is mainly based on the accurate estimates of the incubation period. However, patients…

Associations of procalcitonin, C-reaction protein and neutrophil-to-lymphocyte ratio with mortality in hospitalized COVID-19 patients in China.

Written by Jian-Bo Xu, Chao Xu, Ru-Bing Zhang, Meng Wu, Chang-Kun Pan, Xiu-Jie Li, Qian Wang, Fang-Fang Zeng, Sui Zhu
September 14, 2020

Coronavirus disease 2019 (COVID-19) is an important and urgent threat to global health. Inflammation factors are important for COVID-19 mortality, and we aim to explore whether the baseline levels of…

The Association of Maternal Emotional Status With Child Over-Use of Electronic Devices During the COVID-19 Pandemic.

Written by Xiangrong Guo, Yulai Zhou, Jian Xu, Yuelai Hu, Zhiwei Liu
December 6, 2021

The quarantine during the COVID-19 pandemic may generate high levels of maternal depression/anxiety, and maternal emotional status may affect child behavioral development. Online education during the pandemic may induce child…

Angiotensin-Converting Enzyme 2 Potentiates SARS-CoV-2 Infection by Antagonizing Type I Interferon Induction and Its Down-Stream Signaling Pathway.

Written by Jian Chen, Jian Liu, Zhilu Chen, Haoran Peng, Cuisong Zhu, Daobin Feng, Shuye Zhang, Ping Zhao, Xiaoyan Zhang, Jianqing Xu
July 12, 2022

The innate interferon (IFN) response constitutes the first line of host defense against viral infections. It has been shown that IFN-I/III treatment could effectively contain severe acute respiratory syndrome coronavirus…

Several major issues concerning the environmental transmission and risk prevention of SARS-CoV-2.

Written by Jin Ma, Jian Xu, Xiaoli Zhao, Shouliang Huo, Xiaoli Duan, Yunsong Mu, Ying Wang, Yuan Wei, Jiang Chang, Xiaowei Jin, Fengchang Wu
April 20, 2022

Coronavirus disease 2019 (COVID-19) is the most serious infectious disease pandemic in the world in a century, and has had a serious impact on the health, safety, and social and…

Clinical characteristics, cause analysis and infectivity of COVID-19 nucleic acid repositive patients: A literature review.

Written by Youjiang Li, Danping Ji, Wangyu Cai, Yingying Hu, Yongying Bai, Jianguo Wu, Jian Xu
November 1, 2020

Coronavirus disease 2019 (COVID-19) poses a serious threat to human health and lives. The virus is still spreading throughout the world, and the cumulative number of confirmed cases is increasing.…

Epidemiological and clinical characteristics of discharged patients infected with SARS-CoV-2 on the Qinghai Plateau.

Written by Aiqi Xi, Ma Zhuo, Jingtao Dai, Yuehe Ding, Xiuzhen Ma, Xiaoli Ma, Xiaoyi Wang, Lianmeng Shi, Huanying Bai, Hongying Zheng, Eric Nuermberger, Jian Xu
July 28, 2020

Since the outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, a series of confirmed cases of COVID-19…

Analyzing Socioeconomic Factors and Health Disparity of COVID-19 Spatiotemporal Spread Patterns at Neighborhood Levels in San Diego County

Written by Ming-Hsiang Tsou, Jian Xu, Chii-Dean Lin, Morgan Daniels, Eunjeong Ko, Joseph Gibbons
February 23, 2021

This study analyzed spatiotemporal spread patterns of COVID-19 confirmed cases at the zip code level in the County of San Diego and compared them to neighborhood social and economic factors.…

Inhibition of drug-metabolizing enzymes by Jingyin granules: implications of herb-drug interactions in antiviral therapy.

Written by Feng Zhang, Wei Liu, Jian Huang, Qi-Long Chen, Dan-Dan Wang, Li-Wei Zou, Yong-Fang Zhao, Wei-Dong Zhang, Jian-Guang Xu, Hong-Zhuan Chen, Guang-Bo Ge
June 28, 2021

Jingyin granules, a marketed antiviral herbal medicine, have been recommended for treating H1N1 influenza A virus infection and Coronavirus disease 2019 (COVID-19) in China. To fight viral diseases in a…

Differences in Clinical Features and Laboratory Results between Adults and Children with SARS-CoV-2 Infection.

Written by Xiaoli Li, Yan Rong, Peiyan Zhang, Junli Wang, Liping Qie, Lei Rong, Jian Xu
December 1, 2020

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children accounts for a small proportion of all infections and is usually mild or asymptomatic. There are few studies on the…

A child with household transmitted COVID-19.

Written by Li-Juan Mao, Jian Xu, Zhi-Hao Xu, Xiao-Ping Xia, Bin Li, Jian-Guo He, Peng Zhao, Jian-Wei Pan, Dan Zhang, Yue Su, Yue-Hong Wang, Zhe-Feng Yuan
May 7, 2020

BACKGROUND: Although people of all ages are susceptible to the novel coronavirus infection, which is presently named "Coronavirus Disease 2019" (COVID-19), there has been relatively few cases reported among children.…

Comparison of Face-Touching Behaviors Before and During the Coronavirus Disease 2019 Pandemic.

Written by Yong-Jian Chen, Gang Qin, Jie Chen, Jian-Liang Xu, Ding-Yun Feng, Xiang-Yuan Wu, Xing Li
July 1, 2020

Importance: There is insufficient evidence on the efficacy of masks in the general population for the prevention of coronavirus disease 2019 (COVID-19) in public areas. Therefore, it is imperative to…

A Case Study of Applying Metagenomic Sequencing in Precise Epidemiology for the COVID-19 Pandemic - Sichuan Province, China, 2020.

Written by Jianan Xu, Ye Wang, You Li, Huiping Yang, Ming Pan, Jian Liu, Lina Shi, Yuliang Feng, Li Liu, Jin Li, Li Zhang, Shusen He
November 20, 2020

Distribution and Drug Resistance of Bacterial Pathogens Associated with Lower Respiratory Tract Infection in Children and the Effect of COVID-19 on the Distribution of Pathogens.

Written by Xuan Zhu, Ting Ye, Hong Zhong, Yaxuan Luo, Jian Xu, Qin Zhang, Xiaobo Luo, Qin Wang, Liyuan Zhang, Peipei Song, Jun Zhang
March 29, 2022

By studying the distribution and drug resistance of bacterial pathogens associated with lower respiratory tract infection (LRTI) in children in Chengdu and the effect of the COVID-19 on the distribution…

Epidemiological Characteristics of COVID-19 Outbreak in Yangzhou, China, 2021.

Written by Yu-Dong Zhang, Ding Chen, Lei Hu, Liang Shen, Ren-Yuan Wu, Fu-Ming Cao, Jian-Qiang Xu, Liang Wang
May 6, 2022

Objective: Epidemiological characteristics of COVID-19 outbreak in Yangzhou city caused by the highly contagious Delta variant strain of SARS-CoV-2 virus were investigated in this retrospective descriptive study to provide prevention…

Data_Sheet_1_Soundscape Preference of Urban Residents in China in the Post-pandemic Era.PDF

Written by Jinxuan Liu, Jian Xu, Zhicai Wu, Yuru Cheng, Yuxin Gou, Jesse Ridolfo
December 22, 2021

This research aims to explore the reality of the soundscape preferences of Chinese urban residents in general public landscape in the post-pandemic era, and then to propose design recommendations to…

Response and Duration of Serum Anti-SARS-CoV-2 Antibodies After Inactivated Vaccination Within 160 Days.

Written by Qiu-Yan Xu, Jian-Hang Xue, Yao Xiao, Zhi-Juan Jia, Meng-Juan Wu, Yan-Yun Liu, Wei-Li Li, Xian-Ming Liang, Tian-Ci Yang
December 23, 2021

Background: A vaccine against coronavirus disease 2019 (COVID-19) with highly effective protection is urgently needed. The anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody response and duration after vaccination are…

All five COVID-19 outbreaks during epidemic period of 2020/2021 in China were instigated by asymptomatic or pre-symptomatic individuals.

Written by Caixin Yang, Sihui Zhang, Shan Lu, Jing Yang, Yanpeng Cheng, Yue Liu, Lijun Zhao, Jian Gong, Jianguo Xu
May 21, 2021

INTRODUCTION: The significance of asymptomatic or pre-asymptomatic individuals in driving the COVID-19 epidemic in China or other countries remains uncertain. METHOD: We collected and analyzed all the epidemiologic and virological…

Post-SARS-CoV-2-vaccine shoulder pain: Is it relevant to the vaccine injection? - Correspondence.

Written by Zhenhan Deng, Xiaobo Zhang, Yan Liu, Jie Xiao, Yizi Zheng, Yan Huang, Jian Xu
March 18, 2022

The Experience of the Fight Against COVID-19 in Clinical Laboratory Departments from Chengdu, China.

Written by Qin Wang, Chenggui Liu, Jian Xu, Peipei Song, Shuzhe Yang, Qin Zhang
October 7, 2021

OBJECTIVE: In order to fight against coronavirus disease 2019 (COVID-19) better and to share our experience as a reference for clinical laboratory departments. METHODS: This was a retrospective study conducted…

Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates.

Written by Yi Wang, Sui Fang, Yan Wu, Xi Cheng, Lei-Ke Zhang, Xu-Rui Shen, Shuang-Qu Li, Jian-Rong Xu, Wei-Juan Shang, Zhao-Bing Gao, Bing-Qing Xia
July 22, 2021

Lack of efficiency has been a major problem shared by all currently developed anti-SARS-CoV-2 therapies. Our previous study shows that SARS-CoV-2 structural envelope (2-E) protein forms a type of cation…

Infectivity of SARS-CoV-2 and protection against reinfection in rats.

Written by Dandan Yu, Yanghaopeng Long, Ling Xu, Jian-Bao Han, Jiawei Xi, Jianlin Xu, Lu-Xiu Yang, Xiao-Li Feng, Qing-Cui Zou, Wang Qu, Jiangwei Lin, Ming-Hua Li, Yong-Gang Yao
November 18, 2022

Multiple-Inputs Convolutional Neural Network for COVID-19 Classification and Critical Region Screening From Chest X-ray Radiographs: Model Development and Performance Evaluation.

Written by Zhongqiang Li, Zheng Li, Luke Yao, Qing Chen, Jian Zhang, Xin Li, Ji-Ming Feng, Yanping Li, Jian Xu
October 4, 2022

Background: The COVID-19 pandemic is becoming one of the largest, unprecedented health crises, and chest X-ray radiography (CXR) plays a vital role in diagnosing COVID-19. However, extracting and finding useful…

Response to "A commentary on "post-SARS-CoV-2-vaccine shoulder pain: Is it relevant to the vaccine injection? - Correspondence" (Int J Surg 2022;100:106603)".

Written by Jian Xu, Xiaobo Zhang, Zhnehan Deng
August 17, 2022

Social Media Overload and Anxiety Among University Students During the COVID-19 Omicron Wave Lockdown: A Cross-Sectional Study in Shanghai, China, 2022.

Written by Yangyang Wang, Jian Xu, Tian Xie
January 10, 2023

Objectives: The increase in the intensity of social media use during the COVID-19 lockdown has affected mental health. Therefore, it is of practical implications to explore the association between social…

The Association of Internet Use Intensity and Lifestyle Behaviors During the COVID-19 Pandemic: A Cross-Sectional Study in Chinese Adults.

Written by Yangyang Wang, Jian Xu, Tian Xie
July 13, 2022

The COVID-19 pandemic substantially increased the intensity of internet use in humans, which has made public opinion around health and public perceptions of it more vital, and this phenomenon has…

Relationship between internet use intensity and quality of life in chronic patients during the COVID-19 pandemic: The role of physical exercise and health insurance.

Written by Yangyang Wang, Jian Xu, Tian Xie
September 16, 2022

The internet use intensity of human has increased substantially during the COVID-19 Pandemic, and it is severely impacting the well-being of chronic patients. This study aimed to explore the underlying…

How Social Media Influences Public Attitudes to COVID-19 Governance Policy: An Analysis Based on Cognitive-Affective Model.

Written by Ruixia Han, Jian Xu
August 10, 2022

Introduction: Based on the cognitive-affective model, this paper examines how social media affects the public cognitive and affective factors, further influence their attitudes towards COVID-19 governance policy. Methods: Through an…

Evaluation of the efficacy of four anti-SARS-CoV-2 antibodies after vaccination using kits from two manufacturers: A prospective, longitudinal, cohort study at 11 serial time points within 160 days.

Written by Lin Xie, Qiu-Yan Xu, Xin-Qi Zheng, Jian-Hang Xue, Jian-Jun Niu, Tian-Ci Yang
September 28, 2022

PURPOSE: The accuracy of level of anti- severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies is a great concern. We aimed to compare the efficacy of anti-SARS-CoV-2 antibody detection kits…

Focus on global public health, screening for tuberculosis using colour-coded electronic health signs similar to that employed for screening coronavirus disease 2019 in China.

Written by Jian Xu
February 10, 2023

COVID-19, a blessing in disguise for the Tech sector: Evidence from stock price crash risk.

Written by Ashrafee T Hossain, Abdullah-Al Masum, Jian Xu
March 30, 2023

In this paper we document that although COVID-19 has brought uncertainties to the overall economy, the Technology (tech) sector is the systematic beneficiary of the pandemic. Using a quasi-natural setup,…

Undetectable intrauterine transmission during the first trimester of pregnancy in woman after COVID-19 infection.

Written by Jian Xu, Di Mao, Peiling Liang, Peng Du, Xiaomeng Zhang, Xiaoyan Dang, Haiying Wu, Bing Zhu, Ling Sun
April 26, 2023

Bi-anti therapy for SARS-CoV-2 infection among mild/moderate patients to prevent coronavirus disease 2019 from progressing to severe disease.

Written by Jian Xu
February 6, 2023

Single-step, wash-free digital immunoassay for rapid quantitative analysis of serological antibody against SARS-CoV-2 by photonic resonator absorption microscopy.

Written by Bin Zhao, Congnyu Che, Weijing Wang, Nantao Li, Brian T Cunningham
April 1, 2021

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the cause of Coronavirus Disease 2019 (COVID-19), poses extraordinary threats and complex challenges to global public health. Quantitative measurement of SARS-CoV-2 antibody titer…

Evolving perceptions regarding receiving orthopaedic care during the Coronavirus 2019 (COVID-19) pandemic: a follow-up survey.

Written by Arthur J Only, Megan Reams, Shea Comadoll, Brian P Cunningham
January 4, 2022

As the Coronavirus 2019 (COVID-19) pandemic evolves, it is critical to understand how patients' feelings and perceptions have changed. The aim of this study was to understand current feelings and…

Overcoming the limitations of COVID-19 diagnostics with nanostructures, nucleic acid engineering, and additive manufacturing.

Written by Nantao Li, Bin Zhao, Robert Stavins, Ana Sol Peinetti, Neha Chauhan, Rashid Bashir, Brian T Cunningham, William P King, Yi Lu, Xing Wang, Enrique Valera
November 20, 2021

The COVID-19 pandemic revealed fundamental limitations in the current model for infectious disease diagnosis and serology, based upon complex assay workflows, laboratory-based instrumentation, and expensive materials for managing samples and…

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract.

Written by Fu Sun, Anurup Ganguli, Judy Nguyen, Ryan Brisbin, Krithika Shanmugam, David L Hirschberg, Matthew B Wheeler, Rashid Bashir, David M Nash, Brian T Cunningham
May 5, 2020

Rapid, sensitive and specific detection and reporting of infectious pathogens is important for patient management and epidemic surveillance. We demonstrated a point-of-care system integrated with a smartphone for detecting live…

Rapid Isothermal Amplification and Portable Detection System for SARS-CoV-2

Written by Anurup Ganguli, Ariana Mostafa, Jacob Berger, Mehmet Aydin, Fu Sun, Enrique Valera, Brian T. Cunningham, William P. King, Rashid Bashir
May 21, 2020

The COVID-19 pandemic provides an urgent example where a gap exists between availability of state-of-the-art diagnostics and current needs. As assay details and primer sequences become widely known, many laboratories…

Rapid isothermal amplification and portable detection system for SARS-CoV-2.

Written by Anurup Ganguli, Ariana Mostafa, Jacob Berger, Mehmet Y Aydin, Fu Sun, Sarah A Stewart de Ramirez, Enrique Valera, Brian T Cunningham, William P King, Rashid Bashir
September 15, 2020

The COVID-19 pandemic provides an urgent example where a gap exists between availability of state-of-the-art diagnostics and current needs. As assay protocols and primer sequences become widely known, many laboratories…

A photonic resonator interferometric scattering microscope for label-free detection of nanometer-scale objects with digital precision in point-of-use environments.

Written by Leyang Liu, Joseph Tibbs, Nantao Li, Amanda Bacon, Skye Shepherd, Hankeun Lee, Neha Chauhan, Utkan Demirci, Xing Wang, Brian T Cunningham
May 15, 2023

Label-free detection and digital counting of nanometer-scaled objects such as nanoparticles, viruses, extracellular vesicles, and protein molecules enable a wide range of applications in cancer diagnostics, pathogen detection, and life…

Net-Shaped DNA Nanostructures Designed for Rapid/Sensitive Detection and Potential Inhibition of the SARS-CoV-2 Virus.

Written by Neha Chauhan, Yanyu Xiong, Shaokang Ren, Abhisek Dwivedy, Nicholas Magazine, Lifeng Zhou, Xiaohe Jin, Tianyi Zhang, Brian T Cunningham, Sherwood Yao, Weishan Huang, Xing Wang
July 26, 2022

We present a net-shaped DNA nanostructure (called "DNA Net" herein) design strategy for selective recognition and high-affinity capture of intact SARS-CoV-2 virions through spatial pattern-matching and multivalent interactions between the…

Label-Free Digital Detection of Intact Virions by Enhanced Scattering Microscopy.

Written by Nantao Li, Xiaojing Wang, Joseph Tibbs, Congnyu Che, Ana Sol Peinetti, Bin Zhao, Leyang Liu, Priyash Barya, Laura Cooper, Lijun Rong, Xing Wang, Yi Lu, Brian T Cunningham
February 2, 2022

Several applications in health diagnostics, food, safety, and environmental monitoring require rapid, simple, selective, and quantitatively accurate viral load monitoring. Here, we introduce the first label-free biosensing method that rapidly…

Designer DNA NanoGripper

Written by Lifeng Zhou, Yanyu Xiong, Laura Cooper, Skye Shepherd, Tingjie Song, Abhisek Dwivedy, Lijun Rong, Tong Wang, Brian Cunningham, Xing Wang
April 27, 2023

DNA has shown great biocompatibility, programmable mechanical properties, and structural addressability at the nanometer scale, making it a versatile material for building high precision nanorobotics for biomedical applications. Herein, we…

Rapid detection of intact SARS-CoV-2 using designer DNA Nets and a pocket-size smartphone-linked fluorimeter.

Written by Hankeun Lee, Weijing Wang, Neha Chauhan, Yanyu Xiong, Nicholas Magazine, Owen Valdescruz, Dong Yeun Kim, Tianjie Qiu, Weishan Huang, Xing Wang, Brian T Cunningham
March 16, 2023

Rapid, sensitive, and inexpensive point-of-care diagnosis is vital to controlling highly infectious diseases, including COVID-19. Here, we report the design and characterization of a compact fluorimeter called a "Virus Pod"…

Net-shaped DNA nanostructure designed for rapid/sensitive detection and potential inhibition of SARS-CoV-2 virus

Written by Neha Chauhan, Yanyu Xiong, Shaokang Ren, Abhisek Dwivedy, Nicholas Magazine, Lifeng Zhou, Xiaohe Lin, Tianyi Zhang, Brian T. Cunningham, Sherwood Yao, Weishan Huang, Xing Wang
May 5, 2022

We present a net-shaped DNA nanostructure (called "DNA Net" herein) design strategy for selective recognition and high-affinity capture of the intact SARS-CoV-2 virions through spatial pattern-matching and multivalent interactions between…