RADx-rad / Diagnostics Portal

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Death from COVID-19: management of breathlessness: a retrospective multicentre study.

Written by Colette Reid, Barry Laird, Susan Travers, Jessica McNiff, Suzanne Young, Jack Maddicks, Angela Bentley, Stephen Fenning

October 28, 2021

OBJECTIVES: Breathlessness is the most significant symptom in those dying of COVID-19. Historically, though, it has often been palliated poorly at end of life. The aim of this work was…

Chemosensory losses in past and active likely delta variant break-through COVID-19 cases.

Written by Kym Man, Christopher T Simons, Aayah Mohamed-Osman, Susan P Travers, Kai Zhao

May 16, 2022

Preliminary Recommendations for Surgical Practice of Neurosurgery Department in the Central Epidemic Area of 2019 Coronavirus Infection.

Written by Yu-Tang Tan, Jun-Wen Wang, Kai Zhao, Lin Han, Hua-Qiu Zhang, Hong-Quan Niu, Kai Shu, Ting Lei

March 26, 2020

Since December 2019, an outbreak of coronavirus disease 2019 (COVID-19) has posed significant threats to the public health and life in China. Unlike the other 6 identified coronaviruses, the SARS-Cov-2…

A pneumonia outbreak associated with a new coronavirus of probable bat origin.

Written by Peng Zhou, Xing-Lou Yang, Xian-Guang Wang, Ben Hu, Lei Zhang, Wei Zhang, Hao-Rui Si, Yan Zhu, Bei Li, Chao-Lin Huang, Hui-Dong Chen, Jing Chen, Yun Luo, Hua Guo, Ren-Di Jiang, Mei-Qin Liu, Ying Chen, Xu-Rui Shen, Xi Wang, Xiao-Shuang Zheng, Kai Zhao, Quan-Jiao Chen, Fei Deng, Lin-Lin Liu, Bing Yan, Fa-Xian Zhan, Yan-Yi Wang, Geng-Fu Xiao, Zheng-Li Shi

February 3, 2020

Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural reservoir host, bats1-4. Previous studies…

Broad Cell Tropism of SADS-CoV In Vitro Implies Its Potential Cross-Species Infection Risk.

Written by Yun Luo, Ying Chen, Rong Geng, Bei Li, Jing Chen, Kai Zhao, Xiao-Shuang Zheng, Wei Zhang, Peng Zhou, Xing-Lou Yang, Zheng-Li Shi

November 17, 2020

Impaired spermatogenesis in COVID-19 patients.

Written by Honggang Li, Xingyuan Xiao, Jie Zhang, Mohammad Ishraq Zafar, Chunlin Wu, Yuting Long, Wei Lu, Feng Pan, Tianqing Meng, Kai Zhao, Liquan Zhou, Shiliang Shen, Liang Liu, Qian Liu, Chengliang Xiong

October 23, 2020

BACKGROUND: The current study aimed to determine the impact of SARS-CoV-2 infection on male fertility. METHODS: This is a single-center, hospital-based observational study that included autopsied testicular and epididymal specimens…

Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin

January 23, 2020

Since the SARS outbreak 18 years ago, a large number of severe acute respiratory syndrome related coronaviruses (SARSr-CoV) have been discovered in their natural reservoir host, bats1-4. Previous studies indicated…

Relationship Between Psychological Responses and the Appraisal of Risk Communication During the Early Phase of the COVID-19 Pandemic: A Two-Wave Study of Community Residents in China.

Written by Zheng Jin, Kai-Bin Zhao, Yan-Yu Xia, Rui-Jun Chen, Huan Yu, Timothy Tamunang Tamutana, Zheng Yuan, Yi-Ming Shi, Hanna Yeshinegus Adamseged, Marina Kogay, Gyun Yeol Park

September 30, 2020

The novel coronavirus disease (COVID-19) has affected hundreds of millions of people worldwide. Data collection in the ascending phase is crucial to address a rapidly evolving crisis by helping us…

The Changing Patterns of Consumers' Behavior in China: A Comparison during and after the COVID-19 Pandemic.

Written by Xiaoling Yuan, Caijuan Li, Kai Zhao, Xiaoyu Xu

March 2, 2021

This paper has an opportunity to collect questionnaire-based data regarding respondents' life choices in China at the peak of COVID-19 outbreak (i.e., around 9-11 March 2020) and in a relatively…

The timeline and risk factors of clinical progression of COVID-19 in Shenzhen, China.

Written by Fang Wang, Mengyuan Qu, Xuan Zhou, Kai Zhao, Changxiang Lai, Qiyuan Tang, Wenjie Xian, Ruikun Chen, Xuan Li, Zhiyu Li, Qing He, Lei Liu

July 3, 2020

BACKGROUND: The novel coronavirus disease 2019 (COVID-19) broke out globally. Early prediction of the clinical progression was essential but still unclear. We aimed to evaluate the timeline of COVID-19 development…

Prolonged shedding of severe acute respiratory syndrome coronavirus 2 in patients with COVID-19.

Written by Qian Li, Xiao-Shuang Zheng, Xu-Rui Shen, Hao-Rui Si, Xi Wang, Qi Wang, Bei Li, Wei Zhang, Yan Zhu, Ren-Di Jiang, Kai Zhao, Hui Wang, Zheng-Li Shi, Hui-Lan Zhang, Rong-Hui Du, Peng Zhou

Following acute infection, individuals COVID-19 may still shed SARS-CoV-2 RNA. However, limited information is available regarding the active shedding period or whether infectious virus is also shed. Here, we monitored…

Editorial.

Written by Kai Zhao

Neurosurgery resumption in Wuhan during the early post-epidemic period: what should we pay attention to?

Written by Yiwei Qi, Xiaojin Liu, Xueyan Wan, Liang Lu, Feng Hu, Chunxia Qi, Kai Zhao, Kai Shu, Ting Lei

April 10, 2021

COVID-19 has spread globally, causing a pandemic and medical interruptions. As more countries control the epidemic, the resumption of work is imperative. However, asymptomatic carriers become the main source of…

The clinical characteristics and prognosis of COVID-19 patients with cerebral stroke: A retrospective study of 113 cases from one single-centre.

Written by Xiaolong Yao, Shengwen Liu, Junwen Wang, Kai Zhao, Xiaobing Long, Xuejun He, Huicong Kang, Yiping Yang, Xiaopeng Ma, Pengjie Yue, Kai Shu, Zhouping Tang, Ting Lei, Jihong Liu, Wei Wang, Huaqiu Zhang

December 21, 2020

To explore the clinical characteristics and prognosis of COVID-19 patients with cerebral stroke. A total of 2,474 COVID-19 patients from February 10th to March 24th, 2020 were admitted and treated…

Addendum: A pneumonia outbreak associated with a new coronavirus of probable bat origin.

Engineered Trimeric ACE2 Binds and Locks "Three-up" Spike Protein to Potently Inhibit SARS-CoVs and Mutants

Written by Liang Guo, Wenwen Bi, Xinling Wang, Wei Xu, Renhong Yan, Yuanyuan Zhang, Kai Zhao, Yaning Li, Mingfeng Zhang, Xingyue Bao, Xia Cai, Yutang Li, Di Qu, Shibo Jiang, Youhua Xie, Qiang Zhou, Lu Lu, Bobo Dang

September 1, 2020

SARS-CoV-2 enters cells via ACE-2, which binds the spike protein with moderate affinity. Despite a constant background mutational rate, the virus must retain binding with ACE2 for infectivity, providing a…

Severe Acute Respiratory Syndrome Coronavirus 2 and Male Reproduction: Relationship, Explanations, and Clinical Remedies.

Written by Jia Xu, Liting He, Yuan Zhang, Zhiyong Hu, Yufang Su, Yiwei Fang, Meilin Peng, Zunpan Fan, Chunyan Liu, Kai Zhao, Huiping Zhang

April 14, 2021

Coronavirus disease 2019 (COVID-2019) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been an ongoing pandemic and worldwide public health emergency, having drawn a lot of attention around…

Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection.

Written by Liang Guo, Wenwen Bi, Xinling Wang, Wei Xu, Renhong Yan, Yuanyuan Zhang, Kai Zhao, Yaning Li, Mingfeng Zhang, Xia Cai, Shibo Jiang, Youhua Xie, Qiang Zhou, Lu Lu, Bobo Dang

November 11, 2020

Genetic Mutation of SARS-CoV-2 during Consecutive Passages in Permissive Cells.

Written by Ying Chen, Mei-Qin Liu, Yun Luo, Ren-Di Jiang, Hao-Rui Si, Yan Zhu, Bei Li, Xu-Rui Shen, Hao-Feng Lin, Kai Zhao, Ben Hu, Zheng-Li Shi, Xing-Lou Yang

April 26, 2021

Protective Efficacy of Inactivated Vaccine against SARS-CoV-2 Infection in Mice and Non-Human Primates.

Written by Yan-Feng Yao, Ze-Jun Wang, Ren-Di Jiang, Xue Hu, Hua-Jun Zhang, Yi-Wu Zhou, Ge Gao, Ying Chen, Yun Peng, Mei-Qin Liu, Ya-Nan Zhang, Juan Min, Jia Lu, Xiao-Xiao Gao, Jing Guo, Cheng Peng, Xu-Rui Shen, Qian Li, Kai Zhao, Lian Yang, Xin Wan, Bo Zhang, Wen-Hui Wang, Jia Wu, Peng Zhou, Xing-Lou Yang, Shuo Shen, Chao Shan, Zhi-Ming Yuan, Zheng-Li Shi

April 9, 2021

The ongoing coronavirus disease 2019 (COVID-19) pandemic caused more than 96 million infections and over 2 million deaths worldwide so far. However, there is no approved vaccine available for severe…

Identification of ZDHHC17 as a Potential Drug Target for Swine Acute Diarrhea Syndrome Coronavirus Infection.

Written by Yun Luo, Chee Wah Tan, Shi-Zhe Xie, Ying Chen, Yu-Lin Yao, Kai Zhao, Yan Zhu, Qi Wang, Mei-Qin Liu, Xing-Lou Yang, Lin-Fa Wang, Zheng-Li Shi

October 26, 2021

The recent emergence and spread of zoonotic viruses highlights that animal-sourced viruses are the biggest threat to global public health. Swine acute diarrhea syndrome coronavirus (SADS-CoV) is an HKU2-related bat…

Characteristics of SARS-CoV-2 transmission in a medium-sized city with traditional communities during the early COVID-19 epidemic in China.

Written by Yang Li, Hao-Rui Si, Yan Zhu, Nan Xie, Bei Li, Xiang-Ping Zhang, Jun-Feng Han, Hong-Hong Bao, Yong Yang, Kai Zhao, Zi-Yuan Hou, Si-Jia Cheng, Shuan-Hu Zhang, Zheng-Li Shi, Peng Zhou

January 25, 2022

The nationwide COVID-19 epidemic ended in 2020, a few months after its outbreak in Wuhan, China at the end of 2019. Most COVID-19 cases occurred in Hubei Province, with a…

Cas12a-assisted RTF-EXPAR for accurate, rapid and simple detection of SARS-CoV-2 RNA.

Written by Xiao-Min Hang, Hui-Yi Wang, Peng-Fei Liu, Kai-Ren Zhao, Li Wang

September 6, 2022

Developing highly accurate and simple approaches to rapidly identify and isolate SARS-CoV-2 infected patients is important for the control of the COVID-19 pandemic. We, herein, reported the performance of a…

A Confectionary-based Screening Tool for Assessing Chemosensory Loss in COVID-19 Patients